micelles相关论文
Intelligent self-assembly prodrug micelles loading doxorubicin in response to tumor microenvironment
Compared with physical drug-loaded nanocarriers,polymeric prodrug micelles have many advantages such as high drug loadin......
Micellar Catalysis:Visible-Light Mediated Imidazo[1,2-a]pyridine C—H Amination with N-Aminopyridiniu
A light-promoted metal-free protocol for the amination of imidazo[1,2-a]pyridines with N-aminopyridinium salt by the ass......
An Artificial Light-Harvesting System with Tunable Fluorescence Color in Aqueous Sodium Dodecyl Sulf
In the present work,an artificial light-harvesting system with fluorescence resonance energy transfer (FRET) is successf......
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Four-armed amphiphilic block copolymers, polystyrene-b-poly(N-isopropylacrylamide) (PS-b-PNIPAM)4, were synthesized by a......
Optimization and characterization of deoxypodophyllotoxin loaded mPEG-PDLLA micelles by central comp
The therapeutic application of deoxypodophyllotoxin (DPT) is limited due to its poor water solubility and stability.In t......
The Influence of the Admixed Micelles Based on Triblock Copolymers on Material Properties of Both Fr
In this study, the influence of the micelles prepared by triblock copolymers on the properties of fresh and hardened cem......
Synthesis of phenylboronic ester-linked Y-shape polymer via passerini reaction for ROS-responsive dr
Recently,oxidation-responsive polymers have been demonstrated to be promising for various biomedical applications[1].Amo......
Despite the significant advantages of nano-micellar systems on drug delivery,the poor therapeutic outcome in clinic is a......
We demonstrate a theranostic micelle system for cancer near infrared fluorescent (NIRF) imaging with enhanced signal to ......
Near infrared (NIR) light induced photothermal effect for Fe3O4 nanoparticles, contained in Pluronic F127 micelles, has ......
Gold Nanorod-Cored Micelles as a Remotely-Controllable Near IR-Triggered Drug Release System for Eff
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Dinuclear Platinum (Ⅱ) Loaded Micelles Directed to Reduce Systemic Toxicity and Enhance Antitumor Ac
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pH-Sensitive star-shaped poly(glutamic acid) with a porphyrin core as highly efficient photosensitiz
Photodynamic therapy (PDT) has exhibited a great potential in cancer therapy due to its noninvasive and effective proper......
Dual micelles loaded gelatin nanofibers and their application in lipopolysaccharide-induced periodon
SP600125 and SB203580 have exhibited a great potential in lipopolysaccharide (LPS)-induced periodontal therapy.However,d......
Interface crosslinked poly(ethylene glycoi)-poly(amino acid)s copolymer micelles for reduction-trigg
Polymeric micelles self-assembled from amphiphilic block polymers have been widely used for drug delivery.However,a prac......
Reduction-sensitive micelles with detachable poly (2-ethyl-2-oxazoline) corona for enhanced intracel
Micelles formed from poly (ethylene glycol) (PEG) conjugates through self-assembly have been widely studied for delivery......
Synthesis of hyperbranched polyglycidol-block-poly(L-lactide) for pH-sensitive controlled drug deliv
A series of novel and biocompatible hyperbranched polyglycidol-b-poly(L-lactide) (HBP-b-p(L-lactide)n) (n =10,20,30 and ......
Poly(β-L-malic acid) (PMLA),a natural aliphatic polyester,has been proven to be a promising carrier for anti-cancer dru......
Pluronic 123 modified Fe3O4 nanoparticles co-loading PTX and ZnPc to overcome multidrug resistance i
Multidrug resistance is a worldwide problem that has led to clinical chemotherapy failure.The ATP binding cassette(ABC)-......
Synthesis, Anticoagulant Activity and Potential Drug Carrier of Biomimetic N-Cholesteryl Hemisuccina
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Micelles and vesicles have long been proposed as carriers for low molecular weight molecules including drugs.The ability......
In the middle of the 90s,we made simple degradable microspheres for drug delivery.Using different polymers such as polya......
Redox-sensitive hyaluronic acid-paclitaxel conjugate micelles with high physical drug loading for ef
The design of targeted polymer-drug conjugate capable of controlled drug release remains a benchmark for drug delivery s......
Low-density lipoprotein-coupled N-succinyl chitosan lipoic acid micelles co-delivering siRNA and Pac
Objective: To increase targeting effect and reverse the multiple drug resistance(MDR) on cancer cells by building and in......
Glycyrrhetinic Acid-Decorated and Reduction-Sensitive Micelles for Enhancing Bioavailability and Ant
In the present study, we developed a dual-functional biodegradable micellar system named glycyrrhetinic acid-poly (ethyl......
pH and Redox Dual Responsive Polymeric Micelles for Enhanced Intracellular Drug Release in Cancer Th
To improve the intracellular drug release and anticancer efficacy in cancer therapy, in the present study, a pH and redo......
Targeting E-selectin with a sialic acid-decorated conjugate micelles for ameliorating acute kidney i
Acute kidney injury(AKI)induced by various stressors(e.g.endoxemia and ischemia/reperfusion)is the most common cause of ......
Environmentally sensitive micelles co-delivering drug and siRNA for targeting therapy of proliferati
Previous studies have shown that orthotopic non-small cell lung cancer (NSCLC) showed strong ability of invasion and met......
As the first-line agent for genital warts, Podophyllotoxin (POD) could induce extensively dermal burning, itching, and e......
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Synthesis and characterization of N-caprinoyl-N-arginine chitosan as self-assembled micelles carrier
Objective: Based on natural biodegradable chitosan,we connected arginine to the 6-amino-acid-position of chitosan in ord......
Dual-Functional c(RGDyK)-Decorated Pluronic Micelles for Antiangiogenesis and Drug Resistant Tumor T
Dual-function drug delivery system was developed by decorated c(RGDyK) peptide with Pluronic micelles (c(RGDyK)-FP-DP) t......
Sequential Release Chemotherapeutic Drug with Polymeric Delivery System for Oral Squamous Cell Carci
Purpose: We developed a ROS-responsive effective drug delivery system to overcoming multidrug resistance(MDR)of oral squ......
PH-Responsive Micelles Constructed by PCL-PEG-PCL Triblock copolymer Via Oxime Linkage for Anticance
Purpose: To obtain a pH-responsive Doxorubicin drug delivery system.Methods: A novel and well-defined pH-triggered backb......
Docetaxel loaded Pluronic P105/F127 mixed micelles against Drug-Resistant Lung Adenocarcinoma Cell L
The aim of this study was to investigate the antitumor effect of docetaxel (DTX) loaded Pluronic P105/F127 mixed micelle......
Objective:to promote the application of methoxy poly (ethylene glycol)-cholesterol (mPEG-CHOL) in hydrophobic drugs load......
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Treatment of malignant brain tumors continues to challenge scientists and clinicians alike. Location of these tumors wit......
The goal of the present study is to elucidate the intragastrointestinal fate of micellar delivery systems by monitoring ......
Targeted Micellar Phthalocyanine for Lymph Node Metastasis Homing and Photothermal Therapy in an Ort
Tumor lymph node(LN)metastasis seriously affects the treatment prognosis.Studies have shown that nanoparticles with size......
Targeted Micellar Phthalocyanine for Lymph Node Metastasis Homing and Photothermal Therapy in an Ort
Tumor lymph node (LN) metastasis seriously affects the treatment prognosis. Studies have shown that nanoparticles with s......
Cancer is one of the most serious and lethal diseases around the world.The China incidence of cancer is 2,000,000, l......
This paper describes a robust method for the synthesis of high-quality ZIF-8 nanocrystals using reverse micelles as disc......
Here we described the design and synthesis of a discrete 3D amphiphilic metallacage 4, in which the tetragonal prismatic......
目的:合成双嵌段共聚物材料聚(2-乙基-2-噁唑啉)-聚乳酸(PEOz-PLA),制备紫杉醇pH敏感嵌段共聚物胶束,并对其体外性质进行评价。方......
目的:把生物素接枝到泊洛沙姆上制备包载表柔比星(EPI)的生物素-泊洛沙姆(BP)胶束.方法:分别对包载EPI的BP胶束的粒径、Zeta电位、......
目的 以聚乙二醇单甲醚-聚乳酸(mPEG-PLA)嵌段共聚物为载体材料制备塞来昔布载药胶束,并考察其在大鼠体内药动学情况.方法 采用薄......
In many ways,cancer cells are different from healthy cells.A lot of tactical nano-based drug delivery systems are based ......